InnateDB Protein
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IDBP-598526.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RNASE9
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Protein Name
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ribonuclease, RNase A family, 9 (non-active)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000450800
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InnateDB Gene
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IDBG-2291 (RNASE9)
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Protein Structure
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Function |
Does not exhibit any ribonuclease activity. {ECO:0000269PubMed:18992174, ECO:0000269PubMed:19137000}.
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Subcellular Localization |
Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
At the mRNA level, widely expressed (PubMed:18992174). At protein level, restricted to epididymis (PubMed:19137000). Expressed in spermatozoa (sperm head and neck), with higher levels on ejaculated and epididymal sperm than on testicular sperm (at protein level). Expressed in the epithelial cells of the epididymal tubule (at protein level). Not detected in muscle. {ECO:0000269PubMed:18992174, ECO:0000269PubMed:19137000}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0003676
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nucleic acid binding
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GO:0016892
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endoribonuclease activity, producing 3'-phosphomonoesters
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Biological Process |
GO:0090502
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RNA phosphodiester bond hydrolysis, endonucleolytic
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Cellular Component |
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PDB ID |
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InterPro |
IPR023412
Ribonuclease A-domain
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PFAM |
PF00074
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PRINTS |
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PIRSF |
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SMART |
SM00092
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TIGRFAMs |
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Modification |
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SwissProt |
P60153
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PhosphoSite |
PhosphoSite-
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TrEMBL |
W0UV99
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UniProt Splice Variant |
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Entrez Gene |
390443
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UniGene |
Hs.533972
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RefSeq |
XP_006720205
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HUGO |
HGNC:20673
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OMIM |
614014
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CCDS |
CCDS32036
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HPRD |
17983
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IMGT |
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EMBL |
AF382949
AL163195
AY665804
AY907670
BC130311
BC130313
EF061296
EF061297
EF061298
EF061299
EF061300
EF061301
EF061302
EF061303
EF061304
EU414264
HG328847
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GenPept |
AAI30312
AAI30314
AAQ02792
AAV87182
AAX86045
ABP97451
ABP97452
ABP97453
ABP97454
ABP97455
ABP97456
ABP97457
ABP97458
ABP97459
ACA49544
CDG31923
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