Version 5.4
Homo sapiens Protein: BCAT1
Summary
InnateDB Protein IDBP-598785.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCAT1
Protein Name branched chain amino-acid transaminase 1, cytosolic
Synonyms BCATC; BCT1; ECA39; MECA39; PNAS121; PP18;
Species Homo sapiens
Ensembl Protein ENSP00000443459
InnateDB Gene IDBG-23682 (BCAT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0042802 identical protein binding
GO:0052654 L-leucine transaminase activity
GO:0052655 L-valine transaminase activity
GO:0052656 L-isoleucine transaminase activity
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0008152 metabolic process
GO:0008283 cell proliferation
GO:0009081 branched-chain amino acid metabolic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009083 branched-chain amino acid catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001544 Aminotransferase, class IV
IPR005786 Branched-chain amino acid aminotransferase II
PFAM PF01063
PRINTS
PIRSF PIRSF006468
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P54687
PhosphoSite PhosphoSite-P54687
TrEMBL
UniProt Splice Variant
Entrez Gene 586
UniGene Hs.628296
RefSeq NP_001171564
HUGO HGNC:976
OMIM 113520
CCDS CCDS53761
HPRD 00216
IMGT
EMBL AC023796 AC026310 AC092867 AK056255 AK128527 AK294879 AK299088 CR749308 U21551
GenPept AAB08528 BAB71129 BAG54689 BAH11911 BAH12946 CAH18163

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca