Homo sapiens Protein: CTNNA1
Summary
InnateDB Protein IDBP-598991.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTNNA1
Protein Name catenin (cadherin-associated protein), alpha 1, 102kDa
Synonyms CAP102;
Species Homo sapiens
Ensembl Protein ENSP00000438476
InnateDB Gene IDBG-47369 (CTNNA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 85 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 85 [view]
Protein-Protein 81 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0017166 vinculin binding
GO:0044822 poly(A) RNA binding
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0042692 muscle cell differentiation
GO:0043297 apical junction assembly
GO:0045216 cell-cell junction organization
GO:0051149 positive regulation of muscle cell differentiation
GO:0071681 cellular response to indole-3-methanol
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0015629 actin cytoskeleton
GO:0016342 catenin complex
Protein Structure and Domains
PDB ID
InterPro IPR001033 Alpha-catenin
IPR006077 Vinculin/alpha-catenin
IPR017997 Vinculin
PFAM PF01044
PRINTS PR00805
PR00806
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P35221
PhosphoSite PhosphoSite-P35221
TrEMBL E5RJP7
UniProt Splice Variant
Entrez Gene 1495
UniGene Hs.740112
RefSeq NP_001277241
HUGO HGNC:2509
OMIM 116805
CCDS CCDS75315
HPRD 00285
IMGT
EMBL AC010453 AC011405 AC034243 AC113340 AF102787 AF102788 AF102789 AF102790 AF102791 AF102792 AF102793 AF102794 AF102795 AF102796 AF102797 AF102798 AF102799 AF102800 AF102801 AF102802 AF102803 AY884207 BC000385 BC031262 CH471062 D13866 D14705 HQ589335 L22080 L23805 U03100
GenPept AAA18949 AAA35502 AAA86430 AAC99459 AAH00385 AAH31262 AAW56940 AEF32483 BAA02979 BAA03530 EAW62124