Version 5.4
Homo sapiens Protein: ELSPBP1
Summary
InnateDB Protein IDBP-59925.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELSPBP1
Protein Name epididymal sperm binding protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000340660
InnateDB Gene IDBG-59923 (ELSPBP1)
Protein Structure
UniProt Annotation
Function Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000269PubMed:11144225, ECO:0000269PubMed:17307309}.
Disease Associations
Tissue Specificity Detected in cauda epididymidal fluid and on sperm membrane (at protein level). {ECO:0000269PubMed:11144225, ECO:0000269PubMed:17307309}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007338 single fertilization
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000562 Fibronectin, type II, collagen-binding
IPR013806 Kringle-like fold
PFAM PF00040
PRINTS
PIRSF
SMART SM00059
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96BH3
PhosphoSite PhosphoSite-Q96BH3
TrEMBL M0QZH6
UniProt Splice Variant
Entrez Gene 64100
UniGene Hs.104894
RefSeq NP_071425
HUGO HGNC:14417
OMIM 607443
CCDS CCDS12708
HPRD 12119
IMGT
EMBL AC010330 AF279147 AJ278478 BC015598
GenPept AAH15598 AAK69481 CAC14267

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca