Version 5.4
Homo sapiens Protein: HNF1A
Summary
InnateDB Protein IDBP-599915.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNF1A
Protein Name HNF1 homeobox A
Synonyms HNF-1A; HNF1; IDDM20; LFB1; MODY3; TCF-1; TCF1;
Species Homo sapiens
Ensembl Protein ENSP00000453965
InnateDB Gene IDBG-61093 (HNF1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 357 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 357 [view]
Protein-Protein 50 [view]
Protein-DNA 307 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006899 Hepatocyte nuclear factor 1, N-terminal
IPR009057 Homeodomain-like
IPR010982 Lambda repressor-like, DNA-binding domain
IPR023219 Hepatocyte nuclear factor 1, dimerisation domain
PFAM PF04814
PF13413
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E0YMI8
UniProt Splice Variant
Entrez Gene 6927
UniGene Hs.654455
RefSeq
HUGO HGNC:11621
OMIM 142410
CCDS
HPRD 00800
IMGT
EMBL FJ550192 FJ550194 FJ550195 FJ550197 FJ550200 FJ550201 FJ550202 HM116542
GenPept ACL15382 ACL15384 ACL15385 ACL15387 ACL15390 ACL15391 ACL15392 ADM43482

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca