Version 5.4
Homo sapiens Protein: TAS2R20
Summary
InnateDB Protein IDBP-600290.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAS2R20
Protein Name taste receptor, type 2, member 20
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000441624
InnateDB Gene IDBG-547151 (TAS2R20)
Protein Structure
UniProt Annotation
Function Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007960 Mammalian taste receptor
PFAM PF05296
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P59543
PhosphoSite PhosphoSite-P59543
TrEMBL Q50KF4
UniProt Splice Variant
Entrez Gene 259295
UniGene Hs.686384
RefSeq NP_795370
HUGO HGNC:19109
OMIM 613962
CCDS CCDS8639
HPRD 18157
IMGT
EMBL AB199221 AF494236 AY114092 AY724938 BC100915 BC100916 BC100918 BC113843
GenPept AAI00916 AAI00917 AAI00919 AAI13844 AAM19327 AAM63542 AAU21140 BAD98094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca