Version 5.4
Homo sapiens Protein: MTHFSD
Summary
InnateDB Protein IDBP-600439.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTHFSD
Protein Name methenyltetrahydrofolate synthetase domain containing
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000444003
InnateDB Gene IDBG-45403 (MTHFSD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0009396 folic acid-containing compound biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR002698 5-formyltetrahydrofolate cyclo-ligase
PFAM PF00076
PF01812
PRINTS
PIRSF PIRSF006806
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2M296
PhosphoSite PhosphoSite-Q2M296
TrEMBL H3BVG2
UniProt Splice Variant
Entrez Gene 64779
UniGene Hs.602932
RefSeq NP_001152851
HUGO HGNC:25778
OMIM
CCDS CCDS58490
HPRD 07808
IMGT
EMBL AC009108 AK023060 AK023955 BC112057 BC112059 BC143702 BC143707 CH471114
GenPept AAI12058 AAI12060 AAI43703 AAI43708 BAB14383 BAB14739 EAW95418 EAW95419

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca