Version 5.4
Homo sapiens Protein: PRR7
Summary
InnateDB Protein IDBP-60092.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRR7
Protein Name proline rich 7 (synaptic)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000327168
InnateDB Gene IDBG-60090 (PRR7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities (PSD). Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR021684 Uncharacterised protein family WW domain-binding protein 1
PFAM PF11669
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TB68
PhosphoSite PhosphoSite-Q8TB68
TrEMBL D6RFJ4
UniProt Splice Variant
Entrez Gene 80758
UniGene
RefSeq NP_085044
HUGO HGNC:28130
OMIM
CCDS CCDS4419
HPRD 15186
IMGT
EMBL AC145098 BC004261 BC021240 BC024233 BC033649 CH471195
GenPept AAH04261 AAH21240 AAH24233 AAH33649 EAW84994 EAW84995 EAW84996

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca