Homo sapiens Protein: LRRC1
Summary
InnateDB Protein IDBP-601768.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC1
Protein Name leucine rich repeat containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000435217
InnateDB Gene IDBG-91055 (LRRC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11440998}. Membrane {ECO:0000269PubMed:11440998}; Peripheral membrane protein {ECO:0000269PubMed:11440998}. Note=Localized at the basolateral side of epithelial cells.
Disease Associations
Tissue Specificity Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas. {ECO:0000269PubMed:11440998}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BTT6
PhosphoSite PhosphoSite-Q9BTT6
TrEMBL
UniProt Splice Variant
Entrez Gene 55227
UniGene Hs.732252
RefSeq
HUGO HGNC:14307
OMIM 608195
CCDS
HPRD
IMGT
EMBL AF332199 AF359380 AK001637 AK021896 AL033384 AL513211 BC003193 CH471081
GenPept AAH03193 AAK69623 AAK72246 BAA91801 BAB13929 CAI17358 CAI21666 EAX04430