Version 5.4
Homo sapiens Protein: FOS
Summary
InnateDB Protein IDBP-601970.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOS
Protein Name FBJ murine osteosarcoma viral oncogene homolog
Synonyms AP-1; C-FOS; p55;
Species Homo sapiens
Ensembl Protein ENSP00000452590
InnateDB Gene IDBG-12957 (FOS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 186 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 186 [view]
Protein-Protein 134 [view]
Protein-DNA 49 [view]
Protein-RNA 1 [view]
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000837 Fos transforming protein
IPR004827 Basic-leucine zipper domain
IPR008917 Transcription factor, Skn-1-like, DNA-binding domain
PFAM PF00170
PF07716
PRINTS PR00042
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q76MY9
UniProt Splice Variant
Entrez Gene 2353
UniGene Hs.731317
RefSeq
HUGO HGNC:3796
OMIM 164810
CCDS
HPRD 01275
IMGT
EMBL AB022276 AF111167 AK097379 AK290907 CH471061
GenPept BAA87921 BAF83596 BAG53458 EAW81229

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca