Version 5.4
Homo sapiens Protein: STXBP6
Summary
InnateDB Protein IDBP-602149.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STXBP6
Protein Name syntaxin binding protein 6 (amisyn)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000449379
InnateDB Gene IDBG-4093 (STXBP6)
Protein Structure
UniProt Annotation
Function Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:12145319}. Membrane {ECO:0000269PubMed:12145319}; Peripheral membrane protein {ECO:0000269PubMed:12145319}.
Disease Associations
Tissue Specificity Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney. {ECO:0000269PubMed:12145319}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001388 Synaptobrevin
PFAM PF00957
PRINTS PR00219
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NFX7
PhosphoSite PhosphoSite-Q8NFX7
TrEMBL
UniProt Splice Variant
Entrez Gene 29091
UniGene Hs.598844
RefSeq
HUGO HGNC:19666
OMIM 607958
CCDS CCDS9634
HPRD
IMGT
EMBL AF161505 AF391153 AK096957 AL137164 AL161663 AL834346 BC009499 BC067278 CH471078
GenPept AAF29120 AAH09499 AAH67278 AAM46624 BAC04911 CAD39012 EAW65996 EAW65999 EAW66000 EAW66001

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca