InnateDB Protein
|
IDBP-60279.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
PLGLB2
|
Protein Name
|
plasminogen-like B2
|
Synonyms
|
PLGL; PLGP1; PRGB; PRP-B;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000352458
|
InnateDB Gene
|
IDBG-60277 (PLGLB2)
|
Protein Structure
|
|
Function |
May bind noncovalently to lysine binding sites present in the kringle structures of plasminogen. This may interfere with the binding of fibrin or alpha-2-antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.
|
Subcellular Localization |
Secreted.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
0
|
Protein-DNA |
3
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR003014
PAN-1 domain
IPR003609
Apple-like
|
PFAM |
PF00024
|
PRINTS |
|
PIRSF |
|
SMART |
SM00473
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q02325
|
PhosphoSite |
PhosphoSite-Q02325
|
TrEMBL |
Q53QL7
|
UniProt Splice Variant |
|
Entrez Gene |
5343
|
UniGene |
|
RefSeq |
NP_002656
|
HUGO |
HGNC:9073
|
OMIM |
173340
|
CCDS |
CCDS1999
|
HPRD |
01416
|
IMGT |
|
EMBL |
AC093616
AC111200
BC005379
BC022294
BC109248
M86874
M86875
M86876
M93143
|
GenPept |
AAA60169
AAB06491
AAH05379
AAH22294
AAI09249
AAX82025
AAY24020
|
|
|