Homo sapiens Protein: ASIC1
Summary
InnateDB Protein IDBP-602872.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASIC1
Protein Name amiloride-sensitive cation channel 2, neuronal
Synonyms ACCN2; ASIC; BNaC2;
Species Homo sapiens
Ensembl Protein ENSP00000450247
InnateDB Gene IDBG-32261 (ASIC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005272 sodium channel activity
GO:0005515 protein binding
GO:0015280 ligand-gated sodium channel activity
GO:0044736 acid-sensing ion channel activity
Biological Process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0007165 signal transduction
GO:0009268 response to pH
GO:0034220 ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0050915 sensory perception of sour taste
GO:0055085 transmembrane transport
GO:0070207 protein homotrimerization
GO:0071467 cellular response to pH
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001873 Na+ channel, amiloride-sensitive
IPR004724 Epithelial sodium channel
PFAM PF00858
PRINTS PR01078
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P78348
PhosphoSite PhosphoSite-P78348
TrEMBL
UniProt Splice Variant
Entrez Gene 41
UniGene Hs.274361
RefSeq NP_001243759
HUGO HGNC:100
OMIM 602866
CCDS CCDS58228
HPRD 04182
IMGT
EMBL AC025154 BC013891 BC133707 CH471111 EU078959 HM991481 U78180 U78181
GenPept AAB48980 AAB48981 AAH13891 AAI33708 ABU48925 ADP44689 EAW58118