InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KIF1A

Summary

InnateDB Protein

IDBP-603040.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIF1A

Protein Name

kinesin family member 1A

Synonyms

ATSV; C2orf20; HSN2C; MRD9; SPG30; UNC104;

Species

Homo sapiens

Ensembl Protein

ENSP00000438388

InnateDB Gene

IDBG-84910 (KIF1A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.

Experimentally validated
Total	30 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0007018	microtubule-based movement
GO:0008089	anterograde axon cargo transport
GO:0008152	metabolic process
GO:0008219	cell death

Cellular Component

GO:0005737	cytoplasm
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0043005	neuron projection
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR000253 Forkhead-associated (FHA) domain
IPR001752 Kinesin, motor domain
IPR001849 Pleckstrin homology domain
IPR008984 SMAD/FHA domain
IPR022140 Kinesin protein 1B
IPR022164 Kinesin-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00498
PF00225
PF00169
PF12423
PF12473

PRINTS

PR00380

PIRSF

SMART

SM00240
SM00129
SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt