InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HMHA1

Summary

InnateDB Protein

IDBP-603714.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HMHA1

Protein Name

histocompatibility (minor) HA-1

Synonyms

ARHGAP45; HA-1; HLA-HA1;

Species

Homo sapiens

Ensembl Protein

ENSP00000439601

InnateDB Gene

IDBG-13714 (HMHA1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0046872	metal ion binding

Biological Process

GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0035556	intracellular signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0051056	regulation of small GTPase mediated signal transduction

Cellular Component

GO:0005622	intracellular
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR001060 FCH domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR008936 Rho GTPase activation protein

PFAM

PF00620
PF00611
PF00130

PRINTS

PIRSF

SMART

SM00324
SM00055
SM00109

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q92619