Version 5.4
Homo sapiens Protein: MLL2
Summary
InnateDB Protein IDBP-604062.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLL2
Protein Name myeloid/lymphoid or mixed-lineage leukemia 2
Synonyms AAD10; ALR; CAGL114; KABUK1; KMS; MLL2; MLL4; TNRC21;
Species Homo sapiens
Ensembl Protein ENSP00000435714
InnateDB Gene IDBG-30867 (MLL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR003616 Post-SET domain
PFAM PF00856
PRINTS
PIRSF
SMART SM00317
SM00508
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YEF2
UniProt Splice Variant
Entrez Gene 8085
UniGene Hs.731384
RefSeq
HUGO HGNC:7133
OMIM 602113
CCDS
HPRD 03664
IMGT
EMBL AC011603
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca