Version 5.4
Homo sapiens Protein: COX6A1
Summary
InnateDB Protein IDBP-60539.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX6A1
Protein Name cytochrome c oxidase subunit VIa polypeptide 1
Synonyms COX6A; COX6AL;
Species Homo sapiens
Ensembl Protein ENSP00000229379
InnateDB Gene IDBG-60537 (COX6A1)
Protein Structure
UniProt Annotation
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Localization Mitochondrion inner membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005751 mitochondrial respiratory chain complex IV
Protein Structure and Domains
PDB ID
InterPro IPR001349 Cytochrome c oxidase, subunit VIa
PFAM PF02046
PRINTS
PIRSF PIRSF000277
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12074
PhosphoSite PhosphoSite-P12074
TrEMBL Q9UEG9
UniProt Splice Variant
Entrez Gene 1337
UniGene Hs.369624
RefSeq NP_004364
HUGO HGNC:2277
OMIM 602072
CCDS CCDS9197
HPRD 03644
IMGT
EMBL AK312009 AL021546 BC007723 BC070186 BC107861 CH471054 HE647860 U83701 U83702 X15341
GenPept AAD00554 AAH07723 AAH70186 AAI07862 BAG34947 CAA16494 CAA33392 CCF23108 EAW98190 EAW98191

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca