InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COQ5

Summary

InnateDB Protein

IDBP-60704.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COQ5

Protein Name

coenzyme Q5 homolog, methyltransferase (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000288532

InnateDB Gene

IDBG-60702 (COQ5)

Protein Structure

UniProt Annotation

Function

Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008168	methyltransferase activity

Biological Process

GO:0006744	ubiquinone biosynthetic process
GO:0008152	metabolic process
GO:0032259	methylation
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR004033 UbiE/COQ5 methyltransferase
IPR013216 Methyltransferase type 11
IPR013217 Methyltransferase type 12
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01209
PF08241
PF08242

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5HYK3

PhosphoSite