InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RNF10

Summary

InnateDB Protein

IDBP-60738.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RNF10

Protein Name

ring finger protein 10

Synonyms

RIE2;

Species

Homo sapiens

Ensembl Protein

ENSP00000322242

InnateDB Gene

IDBG-60736 (RNF10)

Protein Structure

UniProt Annotation

Function

Transcriptional factor involved in the regulation of MAG expression. Participates in the peripheral nerve development and Schawnn cell differentiation (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	34 [view]
Protein-Protein	33 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0010626	negative regulation of Schwann cell proliferation
GO:0031643	positive regulation of myelination
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051865	protein autoubiquitination