Version 5.4
Homo sapiens Protein: TM4SF4
Summary
InnateDB Protein IDBP-60769.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TM4SF4
Protein Name transmembrane 4 L six family member 4
Synonyms il-TMP; ILTMP;
Species Homo sapiens
Ensembl Protein ENSP00000305852
InnateDB Gene IDBG-60767 (TM4SF4)
Protein Structure
UniProt Annotation
Function Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Jejunum and liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 1 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042246 tissue regeneration
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008661 L6 membrane
PFAM PF05805
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48230
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 7104
UniGene Hs.593697
RefSeq NP_004608
HUGO HGNC:11856
OMIM 606567
CCDS CCDS46932
HPRD 07585
IMGT
EMBL AK315464 BC001386 BT007430 CH471052 U31449
GenPept AAA74745 AAH01386 AAP36098 BAG37851 EAW78871

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca