Version 5.4
Homo sapiens Protein: TBX10
Summary
InnateDB Protein IDBP-60907.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBX10
Protein Name T-box 10
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000335191
InnateDB Gene IDBG-60905 (TBX10)
Protein Structure
UniProt Annotation
Function Probable transcriptional regulator involved in developmental processes.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00201}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0009653 anatomical structure morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding
PFAM PF00907
PRINTS PR00937
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75333
PhosphoSite PhosphoSite-O75333
TrEMBL
UniProt Splice Variant
Entrez Gene 347853
UniGene Hs.454480
RefSeq NP_005986
HUGO HGNC:11593
OMIM 604648
CCDS CCDS31621
HPRD 06872
IMGT
EMBL AH006177 AY229977 BC113485 BC113487
GenPept AAC23481 AAI13486 AAI13488 AAO73483

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca