Version 5.4
Homo sapiens Protein: MLEC
Summary
InnateDB Protein IDBP-60959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLEC
Protein Name malectin
Synonyms KIAA0152;
Species Homo sapiens
Ensembl Protein ENSP00000228506
InnateDB Gene IDBG-60957 (MLEC)
Protein Structure
UniProt Annotation
Function Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0019899 enzyme binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006457 protein folding
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR021720 Malectin
PFAM PF11721
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14165
PhosphoSite PhosphoSite-Q14165
TrEMBL F5H1S8
UniProt Splice Variant
Entrez Gene 9761
UniGene Hs.743298
RefSeq NP_055545
HUGO HGNC:28973
OMIM 613802
CCDS CCDS9206
HPRD 13781
IMGT
EMBL AC069234 BC000371 BC016297 D63486
GenPept AAH00371 AAH16297 BAA09773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca