Version 5.4
Homo sapiens Protein: MAMSTR
Summary
InnateDB Protein IDBP-60977.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAMSTR
Protein Name MEF2 activating motif and SAP domain containing transcriptional regulator
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000324175
InnateDB Gene IDBG-60975 (MAMSTR)
Protein Structure
UniProt Annotation
Function Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in skeletal muscle, brain, placenta and spleen. {ECO:0000269PubMed:16818234}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001076 RNA polymerase II transcription factor binding transcription factor activity
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0010831 positive regulation of myotube differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003034 SAP domain
PFAM PF02037
PRINTS
PIRSF
SMART SM00513
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZN01
PhosphoSite PhosphoSite-Q6ZN01
TrEMBL
UniProt Splice Variant
Entrez Gene 284358
UniGene Hs.191815
RefSeq NP_001124387
HUGO HGNC:26689
OMIM 610349
CCDS CCDS46137
HPRD 08204
IMGT
EMBL AK093389 AK131427 BC105056 BC105058 BC106047 BC143443 CH471177
GenPept AAI05057 AAI05059 AAI06048 AAI43444 BAC04152 BAD18574 EAW52390 EAW52392

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca