InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNAJC1

Summary

InnateDB Protein

IDBP-61105.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNAJC1

Protein Name

DnaJ (Hsp40) homolog, subfamily C, member 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000366179

InnateDB Gene

IDBG-61103 (DNAJC1)

Protein Structure

UniProt Annotation

Function

May modulate protein synthesis. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus membrane; Single-pass type I membrane protein. Microsome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001671	ATPase activator activity
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0051087	chaperone binding

Biological Process

GO:0006417	regulation of translation
GO:0006457	protein folding
GO:0032781	positive regulation of ATPase activity
GO:0045861	negative regulation of proteolysis
GO:0050708	regulation of protein secretion

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031965	nuclear membrane