Version 5.4
Homo sapiens Protein: COMMD3
Summary
InnateDB Protein IDBP-61363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COMMD3
Protein Name COMM domain containing 3
Synonyms BUP; C10orf8;
Species Homo sapiens
Ensembl Protein ENSP00000366032
InnateDB Gene IDBG-61361 (COMMD3)
Protein Structure
UniProt Annotation
Function May down-regulate activation of NF-kappa-B. {ECO:0000269PubMed:15799966}.
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed with highest expression in thymus. {ECO:0000269PubMed:15799966}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR009886 HCaRG
PFAM PF07258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UBI1
PhosphoSite PhosphoSite-Q9UBI1
TrEMBL
UniProt Splice Variant
Entrez Gene 23412
UniGene
RefSeq NP_036203
HUGO HGNC:23332
OMIM
CCDS CCDS7137
HPRD 13082
IMGT
EMBL AF078848 AF201948 AL158211 AY542159 BC022898 CH471072
GenPept AAD44480 AAF17240 AAH22898 AAS22241 CAI15951 EAW86149 EAW86155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca