Version 5.4
| Homo sapiens Protein: GPR87 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-61522.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GPR87 | ||||||||
| Protein Name | G protein-coupled receptor 87 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000260843 | ||||||||
| InnateDB Gene | IDBG-61520 (GPR87) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. {ECO:0000269PubMed:17905198, ECO:0000269PubMed:19602589}. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung. {ECO:0000269PubMed:17905198}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR005466 P2Y14 purinoceptor IPR008109 P2Y13 purinoceptor IPR017452 GPCR, rhodopsin-like, 7TM |
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| PFAM |
PF00001
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| PRINTS |
PR00237
PR01655 PR01735 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9BY21 | ||||||||
| PhosphoSite | PhosphoSite-Q9BY21 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 53836 | ||||||||
| UniGene | Hs.666745 | ||||||||
| RefSeq | NP_076404 | ||||||||
| HUGO | HGNC:4538 | ||||||||
| OMIM | 606379 | ||||||||
| CCDS | CCDS3157 | ||||||||
| HPRD | 16209 | ||||||||
| IMGT | |||||||||
| EMBL | AB031548 AF237763 AF345566 AF411114 AK027784 BC009540 BC112941 BC117565 BC132888 BC132890 CH471052 EU883576 | ||||||||
| GenPept | AAH09540 AAI12942 AAI17566 AAI32889 AAI32891 AAK01858 AAK29069 AAL26485 ACG60650 BAB55366 BAD83583 EAW78808 | ||||||||