Version 5.4
Homo sapiens Protein: CGB
Summary
InnateDB Protein IDBP-61756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CGB
Protein Name chorionic gonadotropin, beta polypeptide
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000349954
InnateDB Gene IDBG-61752 (CGB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed in placenta, testis and pituitary. {ECO:0000269PubMed:16123088, ECO:0000269PubMed:18048458}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0007292 female gamete generation
GO:0016486 peptide hormone processing
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001545 Gonadotropin, beta subunit
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR029034 Cystine-knot cytokine
PFAM PF00007
PRINTS
PIRSF
SMART SM00068
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NT52
PhosphoSite PhosphoSite-Q6NT52
TrEMBL K7ELM3
UniProt Splice Variant
Entrez Gene 94115
UniGene
RefSeq NP_000728
HUGO HGNC:1886
OMIM 608827
CCDS CCDS12749
HPRD 00343
IMGT
EMBL AC008687 AF397576 AF397577 AF397578 AF397579 AF397580 AF397581 AK291552 BC006290 BC022796 BC030994 BC041054 BC051378 BC069367 BC069526 BC103969 BC103970 BC103971 BC106059 BC106723 BC106724 BC128603 BT006890 CH471177 J00117 K00092 K03182 K03183 K03187 K03188 K03189 M13503 M13504 M13505 X00265 X00266
GenPept AAA52005 AAA52008 AAA52009 AAA53287 AAA53288 AAA96690 AAH06290 AAH22796 AAH30994 AAH41054 AAH51378 AAH69367 AAH69526 AAI03970 AAI03971 AAI03972 AAI06060 AAI06724 AAI06725 AAI28604 AAL69704 AAL69705 AAL69706 AAL69707 AAL69708 AAL69709 AAP35536 BAF84241 CAA25068 CAA25069 EAW52434 EAW52437 EAW52438 EAW52439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca