Version 5.4
Homo sapiens Protein: TUBD1
Summary
InnateDB Protein IDBP-61864.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBD1
Protein Name tubulin, delta 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000342561
InnateDB Gene IDBG-61856 (TUBD1)
Protein Structure
UniProt Annotation
Function In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm. Nucleus. Note=Associated with centrioles. Both cytoplasmic and nuclear.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007017 microtubule-based process
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0051258 protein polymerization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005874 microtubule
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR002967 Delta tubulin
IPR003008 Tubulin/FtsZ, GTPase domain
IPR008280 Tubulin/FtsZ, C-terminal
PFAM PF00091
PRINTS PR01224
PIRSF
SMART SM00864
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJT1
PhosphoSite PhosphoSite-Q9UJT1
TrEMBL
UniProt Splice Variant
Entrez Gene 51174
UniGene Hs.635983
RefSeq
HUGO HGNC:16811
OMIM 607344
CCDS
HPRD 06297
IMGT
EMBL AB030837 AB031045 AC004686 AF201333 AK024096 AK298492 AK301312 BC000258 CH471109
GenPept AAF09584 AAH00258 BAB14825 BAD16590 BAD83581 BAG60700 BAG62863 EAW94385 EAW94387

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca