InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PHACTR1

Summary

InnateDB Protein

IDBP-61966.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHACTR1

Protein Name

phosphatase and actin regulator 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000329880

InnateDB Gene

IDBG-61960 (PHACTR1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0004864	protein phosphatase inhibitor activity

Biological Process

GO:0031032	actomyosin structure organization
GO:0031532	actin cytoskeleton reorganization
GO:0043086	negative regulation of catalytic activity
GO:0043149	stress fiber assembly
GO:0048870	cell motility

Cellular Component

GO:0005634	nucleus
GO:0005829	cytosol
GO:0030054	cell junction
GO:0045202	synapse

Protein Structure and Domains

PDB ID

InterPro

IPR004018 RPEL repeat

PFAM

PF02755

PRINTS

PIRSF

SMART

SM00707

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB051520 AK090769 AK290017 AL008729 AL354680 AL391385 AL591682 BC101526 BC101528 Z99495

GenPept

AAI01527 AAI01529 BAB21824 BAF82706 BAG52223 CAI20986 CAI40399 CAI41067 CAI95669

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca