InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Carns1

Summary

InnateDB Protein

IDBP-619815.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Carns1

Protein Name

carnosine synthase 1

Synonyms

AI790298; Atpgd1; mKIAA1394;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131624

InnateDB Gene

IDBG-129138 (Carns1)

Protein Structure

UniProt Annotation

Function

Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine. {ECO:0000269PubMed:20097752}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0046872	metal ion binding
GO:0047730	carnosine synthase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0035499	carnosine biosynthetic process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:2147595

InterPro

IPR011761 ATP-grasp fold
IPR016185 Pre-ATP-grasp domain

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6ZPS2

PhosphoSite

PhosphoSite-Q6ZPS2

TrEMBL

E9PX09

UniProt Splice Variant

Entrez Gene

107239

UniGene

Mm.482310

RefSeq

NP_598909

MGI ID

MGI Symbol

Carns1

OMIM

CCDS

CCDS50350

HPRD

IMGT

EMBL

AC109138 AK129347 BC019736 BC023699

GenPept

AAH19736 AAH23699 BAC98157