Version 5.4
Mus musculus Protein: Esrra
Summary
InnateDB Protein IDBP-619871.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esrra
Protein Name estrogen related receptor, alpha
Synonyms Err1; ERRalpha; Estrra; Nr3b1;
Species Mus musculus
Ensembl Protein ENSMUSP00000134587
InnateDB Gene IDBG-137086 (Esrra)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0019904 protein domain specific binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0042127 regulation of cell proliferation
GO:0043401 steroid hormone mediated signaling pathway
GO:0045667 regulation of osteoblast differentiation
GO:0045670 regulation of osteoclast differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051216 cartilage development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1346831
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF00104
PRINTS PR00398
PIRSF
SMART SM00430
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UZQ2
UniProt Splice Variant
Entrez Gene 26379
UniGene Mm.386776
RefSeq
MGI ID
MGI Symbol Esrra
OMIM
CCDS
HPRD
IMGT
EMBL AC120557
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca