InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Esrra

Summary

InnateDB Protein

IDBP-619872.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Esrra

Protein Name

estrogen related receptor, alpha

Synonyms

Err1; ERRalpha; Estrra; Nr3b1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133916

InnateDB Gene

IDBG-137086 (Esrra)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0019904	protein domain specific binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0042127	regulation of cell proliferation
GO:0045667	regulation of osteoblast differentiation
GO:0045670	regulation of osteoclast differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051216	cartilage development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1346831

InterPro

IPR001628 Zinc finger, nuclear hormone receptor-type

PFAM

PF00105

PRINTS

PR00047

PIRSF

SMART

SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UY24

UniProt Splice Variant

Entrez Gene

26379

UniGene

Mm.386776

RefSeq

MGI ID

MGI Symbol

Esrra

OMIM

CCDS

HPRD

IMGT

EMBL

AC120557

GenPept