InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pkp1

Summary

InnateDB Protein

IDBP-619963.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pkp1

Protein Name

plakophilin 1

Synonyms

AI528551;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128418

InnateDB Gene

IDBG-195134 (Pkp1)

Protein Structure

UniProt Annotation

Function

Seems to play a role in junctional plaques. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cell junction, desmosome {ECO:0000250}. Note=Nuclear and associated with desmosomes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0005521	lamin binding

Biological Process

GO:0016337	single organismal cell-cell adhesion
GO:0045110	intermediate filament bundle assembly

Cellular Component

GO:0005634	nucleus
GO:0030057	desmosome

Protein Structure and Domains

PDB ID

MGI:1328359

InterPro

IPR000225 Armadillo
IPR016024 Armadillo-type fold

PFAM

PF00514

PRINTS

PIRSF

SMART

SM00185

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P97350

PhosphoSite

PhosphoSite-P97350

TrEMBL

UniProt Splice Variant

Entrez Gene

18772

UniGene

Mm.4494

RefSeq

MGI ID

MGI Symbol

Pkp1

OMIM

CCDS

CCDS15322

HPRD

IMGT

EMBL

BC139041 BC139042 Y07941

GenPept

AAI39042 AAI39043 CAA69240