Version 5.4
Mus musculus Protein: Ampd3
Summary
InnateDB Protein IDBP-620016.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ampd3
Protein Name adenosine monophosphate deaminase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000130495
InnateDB Gene IDBG-206642 (Ampd3)
Protein Structure
UniProt Annotation
Function AMP deaminase plays a critical role in energy metabolism.
Subcellular Localization
Disease Associations
Tissue Specificity Found in heart, lung brain, spleen, kidney and to a lesser extent in liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006188 IMP biosynthetic process
GO:0032264 IMP salvage
GO:0046031 ADP metabolic process
GO:0046033 AMP metabolic process
GO:0046034 ATP metabolic process
GO:0097009 energy homeostasis
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1096344
InterPro IPR001365 Adenosine/AMP deaminase domain
IPR006329 AMP deaminase
PFAM PF00962
PRINTS
PIRSF PIRSF001251
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O08739
PhosphoSite PhosphoSite-O08739
TrEMBL Q922J7
UniProt Splice Variant
Entrez Gene 11717
UniGene Mm.445600
RefSeq
MGI ID
MGI Symbol Ampd3
OMIM
CCDS CCDS21747
HPRD
IMGT
EMBL AC122844 AK133465 BC007183 BC040366 BC056380 CH466531 D85596 D88994
GenPept AAH07183 AAH40366 AAH56380 BAA19933 BAA32548 BAE21671 EDL16988 EDL16989 EDL16990

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca