InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc35b3

Summary

InnateDB Protein

IDBP-620260.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc35b3

Protein Name

solute carrier family 35, member B3

Synonyms

4921526O06Rik; AI428480; CGI-19; PABST2; PAPST2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126016

InnateDB Gene

IDBG-146166 (Slc35b3)

Protein Structure

UniProt Annotation

Function

Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0055085

transmembrane transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005739	mitochondrion
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1913978

InterPro

IPR013657 UAA transporter

PFAM

PF08449

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q922Q5

PhosphoSite

PhosphoSite-Q922Q5

TrEMBL

UniProt Splice Variant

Entrez Gene

108652

UniGene

Mm.255506

RefSeq

NP_598821

MGI ID

MGI Symbol

Slc35b3

OMIM

CCDS

CCDS26466

HPRD

IMGT

EMBL

AK076592 AK077208 AK141280 BC006881

GenPept

AAH06881 BAC36405 BAC36684 BAE24633