InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppp2r1a

Summary

InnateDB Protein

IDBP-620869.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppp2r1a

Protein Name

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform

Synonyms

6330556D22Rik; PP2A; PR65;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133334

InnateDB Gene

IDBG-141714 (Ppp2r1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 162 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	41 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	162 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004722	protein serine/threonine phosphatase activity
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0070262	peptidyl-serine dephosphorylation
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0000159	protein phosphatase type 2A complex
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1926334

InterPro

IPR000357 HEAT
IPR016024 Armadillo-type fold
IPR021133 HEAT, type 2

PFAM

PF02985

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UWL2

UniProt Splice Variant

Entrez Gene

51792

UniGene

Mm.473300

RefSeq

MGI ID

MGI Symbol

Ppp2r1a

OMIM

CCDS

HPRD

IMGT

EMBL

AC109204

GenPept