Homo sapiens Protein: ZNF81 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-62087.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | ZNF81 | ||||||||||
Protein Name | zinc finger protein 81 | ||||||||||
Synonyms | |||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Protein | ENSP00000341151 | ||||||||||
InnateDB Gene | IDBG-62079 (ZNF81) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | May be involved in transcriptional regulation. | ||||||||||
Subcellular Localization | Nucleus {ECO:0000305}. | ||||||||||
Disease Associations | Mental retardation, X-linked 45 (MRX45) [MIM:300498]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non- syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. {ECO:0000269PubMed:15121780}. Note=The disease is caused by mutations affecting the gene represented in this entry.Note=A chromosomal aberration involving ZNF81 is found in a severe mental retardation patient. Translocation t(X;9)(p11.23;q34.3). | ||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR001909
Krueppel-associated box IPR007087 Zinc finger, C2H2 IPR015880 Zinc finger, C2H2-like |
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PFAM |
PF01352
PF00096 |
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PRINTS | |||||||||||
PIRSF | |||||||||||
SMART |
SM00349
SM00355 |
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | P51508 | ||||||||||
PhosphoSite | PhosphoSite-P51508 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 347344 | ||||||||||
UniGene | Hs.114246 | ||||||||||
RefSeq | NP_009068 | ||||||||||
HUGO | HGNC:13156 | ||||||||||
OMIM | 314998 | ||||||||||
CCDS | CCDS43933 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AL022578 AL591394 AY487248 X68011 Z98304 | ||||||||||
GenPept | AAS17752 CAA48148 CAI39462 CAI42739 CAI42943 | ||||||||||