Version 5.4
Mus musculus Protein: Cxxc4
Summary
InnateDB Protein IDBP-620877.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cxxc4
Protein Name CXXC finger 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000128574
InnateDB Gene IDBG-195082 (Cxxc4)
Protein Structure
UniProt Annotation
Function Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1. {ECO:0000269PubMed:11113207}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0016055 Wnt signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0016023 cytoplasmic membrane-bounded vesicle
Protein Structure and Domains
PDB ID MGI:2442112
InterPro IPR002857 Zinc finger, CXXC-type
PFAM PF02008
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NXI8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 319478
UniGene Mm.457442
RefSeq
MGI ID
MGI Symbol Cxxc4
OMIM
CCDS
HPRD
IMGT
EMBL BC067052 BC082332
GenPept AAH67052 AAH82332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca