Version 5.4
Mus musculus Protein: Actn1
Summary
InnateDB Protein IDBP-620941.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Actn1
Protein Name actinin, alpha 1
Synonyms 3110023F10Rik; Actn1a;
Species Mus musculus
Ensembl Protein ENSMUSP00000127176
InnateDB Gene IDBG-153380 (Actn1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 78 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003725 double-stranded RNA binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0051017 actin filament bundle assembly
GO:0051764 actin crosslink formation
Cellular Component
GO:0005916 fascia adherens
GO:0030018 Z disc
Protein Structure and Domains
PDB ID MGI:2137706
InterPro IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR002048 EF-hand domain
IPR014837 EF-hand, Ca insensitive
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF00435
PF00036
PF13202
PF13405
PF08726
PF11971
PRINTS
PIRSF
SMART SM00033
SM00054
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A1BN54
UniProt Splice Variant
Entrez Gene 109711
UniGene Mm.407317
RefSeq
MGI ID
MGI Symbol Actn1
OMIM
CCDS
HPRD
IMGT
EMBL AC108401 CT030161 DQ288940
GenPept ABB88726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca