InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Srsf5

Summary

InnateDB Protein

IDBP-620987.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Srsf5

Protein Name

serine/arginine-rich splicing factor 5

Synonyms

Sfrs5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131323

InnateDB Gene

IDBG-154042 (Srsf5)

Protein Structure

UniProt Annotation

Function

May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre- mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	85 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0050733	RS domain binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0009611	response to wounding
GO:0051726	regulation of cell cycle