Version 5.4
| Mus musculus Protein: Ralgps2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-621139.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ralgps2 | ||||||||
| Protein Name | Ral GEF with PH domain and SH3 binding motif 2 | ||||||||
| Synonyms | 1810020P17Rik; 2210408F11Rik; 4921528G01Rik; 9130014M22Rik; AU043409; AW046161; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000132533 | ||||||||
| InnateDB Gene | IDBG-200478 (Ralgps2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion. {ECO:0000269PubMed:17462626}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000269PubMed:17462626}. Cell membrane {ECO:0000269PubMed:17462626}. Note=Associates with membranes through the PH domain. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Abundant in brain and testis. {ECO:0000269PubMed:17462626}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1925505 | ||||||||
| InterPro |
IPR001849
Pleckstrin homology domain IPR001895 Guanine-nucleotide dissociation stimulator CDC25 IPR023578 Ras guanine nucleotide exchange factor, domain |
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| PFAM |
PF00169
PF00617 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00233
SM00147 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9ERD6 | ||||||||
| PhosphoSite | PhosphoSite-Q9ERD6 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 78255 | ||||||||
| UniGene | Mm.409377 | ||||||||
| RefSeq | NP_001153440 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Ralgps2 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS48405 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF312924 AK018622 AK033549 AK036803 AK169368 BC043132 BC052663 | ||||||||
| GenPept | AAG34162 AAH43132 AAH52663 BAB31312 BAC28351 BAC29580 BAE41116 | ||||||||