InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptpro

Summary

InnateDB Protein

IDBP-621535.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptpro

Protein Name

protein tyrosine phosphatase, receptor type, O

Synonyms

D28; GLEPP1; PTPBK; Ptpn15; PTPoc; PTPphi; PTPROt; PTPU2; R-PTP-O;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131764

InnateDB Gene

IDBG-195285 (Ptpro)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0002548	monocyte chemotaxis
GO:0003105	negative regulation of glomerular filtration
GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0032835	glomerulus development
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1097152

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102

PRINTS

PR00700

PIRSF

SMART

SM00194
SM00404

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt