InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nup155

Summary

InnateDB Protein

IDBP-621660.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nup155

Protein Name

nucleoporin 155

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128819

InnateDB Gene

IDBG-128404 (Nup155)

Protein Structure

UniProt Annotation

Function

Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Nucleoplasmic side {ECO:0000250}. Note=In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017056	structural constituent of nuclear pore

Biological Process

GO:0006406	mRNA export from nucleus
GO:0006606	protein import into nucleus
GO:0006998	nuclear envelope organization
GO:0086014	atrial cardiac muscle cell action potential