InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rnf168

Summary

InnateDB Protein

IDBP-621685.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rnf168

Protein Name

ring finger protein 168

Synonyms

3110001H15Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126484

InnateDB Gene

IDBG-153957 (Rnf168)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0031491	nucleosome binding
GO:0042393	histone binding
GO:0043130	ubiquitin binding
GO:0070530	K63-linked polyubiquitin binding

Biological Process

GO:0006302	double-strand break repair
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006974	cellular response to DNA damage stimulus
GO:0010212	response to ionizing radiation
GO:0016567	protein ubiquitination
GO:0035518	histone H2A monoubiquitination
GO:0036351	histone H2A-K13 ubiquitination
GO:0036352	histone H2A-K15 ubiquitination
GO:0045190	isotype switching
GO:0045739	positive regulation of DNA repair
GO:0045900	negative regulation of translational elongation
GO:0070534	protein K63-linked ubiquitination
GO:0070535	histone H2A K63-linked ubiquitination