Version 5.4
Mus musculus Protein: Fyttd1
Summary
InnateDB Protein IDBP-621783.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fyttd1
Protein Name forty-two-three domain containing 1
Synonyms 2010005M05Rik; 3830411L18Rik; 3830421F13Rik; 4933423A17Rik; AI098218; AW539567; C85190;
Species Mus musculus
Ensembl Protein ENSMUSP00000131446
InnateDB Gene IDBG-154880 (Fyttd1)
Protein Structure
UniProt Annotation
Function Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4 (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
Biological Process
GO:0006406 mRNA export from nucleus
Cellular Component
GO:0005654 nucleoplasm
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID MGI:1917955
InterPro IPR009782 Protein of unknown function DUF1346
PFAM PF07078
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91Z49
PhosphoSite PhosphoSite-Q91Z49
TrEMBL
UniProt Splice Variant
Entrez Gene 69823
UniGene Mm.471927
RefSeq NP_001152821
MGI ID
MGI Symbol Fyttd1
OMIM
CCDS CCDS49833
HPRD
IMGT
EMBL AJ344096 AK014447 AK029785 AK050448 AK050479 AK077184 AK139638 AK157602 AK161252 AK166032 AK167564 AK170511 BC010204 BC028253
GenPept AAH10204 AAH28253 BAB29357 BAC26615 BAC34260 BAC34279 BAC36666 BAE24091 BAE34132 BAE36271 BAE38533 BAE39627 BAE41848 CAC51437

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca