Version 5.4
| Mus musculus Protein: Gpr35 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-621813.2 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | Gpr35 | ||||
| Protein Name | G protein-coupled receptor 35 | ||||
| Synonyms | KPG_007; | ||||
| Species | Mus musculus | ||||
| Ensembl Protein | ENSMUSP00000126914 | ||||
| InnateDB Gene | IDBG-181998 (Gpr35) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. {ECO:0000269PubMed:16754668}. | ||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||
| Disease Associations | |||||
| Tissue Specificity | Predominantly expressed in immune and gastrointestinal tissues. {ECO:0000269PubMed:16754668}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | MGI:1929509 | ||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx |
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| PFAM |
PF00001
PF10320 |
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| PRINTS |
PR00237
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| PIRSF | |||||
| SMART | |||||
| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q9ES90 | ||||
| PhosphoSite | PhosphoSite- | ||||
| TrEMBL | Q3TBY9 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 64095 | ||||
| UniGene | Mm.152780 | ||||
| RefSeq | NP_071715 | ||||
| MGI ID | |||||
| MGI Symbol | Gpr35 | ||||
| OMIM | |||||
| CCDS | CCDS15182 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AF200349 AK170995 BC027429 CH466520 | ||||
| GenPept | AAG18487 AAH27429 BAE42168 EDL39976 EDL39977 EDL39978 | ||||