Version 5.4
Mus musculus Protein: Dpy19l2
Summary
InnateDB Protein IDBP-621904.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dpy19l2
Protein Name dpy-19-like 2 (C. elegans)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000132092
InnateDB Gene IDBG-489116 (Dpy19l2)
Protein Structure
UniProt Annotation
Function Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins. Required during spermatogenesis for sperm head elongation and acrosome formation (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Predominantly expressed in testis. Present in testis but absent from epididymal sperm (at protein level). {ECO:0000269PubMed:21397064}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0007275 multicellular organismal development
GO:0007286 spermatid development
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005637 nuclear inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2444662
InterPro IPR018732 Dpy-19
PFAM PF10034
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P0CW70
PhosphoSite PhosphoSite-P0CW70
TrEMBL
UniProt Splice Variant
Entrez Gene 320752
UniGene Mm.46158
RefSeq NP_001159679
MGI ID
MGI Symbol Dpy19l2
OMIM
CCDS CCDS52743
HPRD
IMGT
EMBL AC154463 CT025664
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca