InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: USP32

Summary

InnateDB Protein

IDBP-62218.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP32

Protein Name

ubiquitin specific peptidase 32

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000300896

InnateDB Gene

IDBG-62216 (USP32)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Golgi apparatus {ECO:0000269PubMed:20549504}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0005509	calcium ion binding
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016579	protein deubiquitination

Cellular Component

GO:0005794	Golgi apparatus
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR002048 EF-hand domain
IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
IPR029071 Ubiquitin-related domain

PFAM

PF00443
PF00036
PF13202
PF13405
PF06337

PRINTS

PIRSF

SMART

SM00054
SM00695

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8NFA0