InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccr9

Summary

InnateDB Protein

IDBP-622359.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccr9

Protein Name

chemokine (C-C motif) receptor 9

Synonyms

A130091K22Rik; Cmkbr10; GPR-9-6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126758

InnateDB Gene

IDBG-206422 (Ccr9)

Protein Structure

UniProt Annotation

Function

Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Highly expressed in the thymus and low in lymph nodes and spleen.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0016493	C-C chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0006955	immune response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1341902

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR001277 CXC chemokine receptor 4
IPR001718 CC chemokine receptor 7
IPR004069 CC chemokine receptor 9
IPR005383 CC chemokine receptor like 1
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS