Version 5.4
Mus musculus Protein: Scyl3
Summary
InnateDB Protein IDBP-622567.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scyl3
Protein Name SCY1-like 3 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000132109
InnateDB Gene IDBG-202190 (Scyl3)
Protein Structure
UniProt Annotation
Function May play a role in regulating cell adhesion/migration complexes in migrating cells.
Subcellular Localization Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005488 binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0008150 biological_process
Cellular Component
GO:0005794 Golgi apparatus
GO:0030027 lamellipodium
Protein Structure and Domains
PDB ID MGI:1921385
InterPro IPR000719 Protein kinase domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR016024 Armadillo-type fold
PFAM PF00069
PRINTS
PIRSF
SMART SM00220
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DBQ7
PhosphoSite PhosphoSite-Q9DBQ7
TrEMBL Q8C8F4
UniProt Splice Variant
Entrez Gene 240880
UniGene Mm.389213
RefSeq NP_001272931
MGI ID
MGI Symbol Scyl3
OMIM
CCDS CCDS69967
HPRD
IMGT
EMBL AK004809 AK044100 AK047267 AK050999 AK162937 BC043085 BC066800
GenPept AAH43085 BAB23580 BAC31777 BAC33007 BAC34492 BAE37123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca